What does SkinCeuticals Discoloration Defense Serum do?

A daily serum formulated to reduce dark spots, melasma and uneven skin tone using tranexamic acid, niacinamide and HEPES.

How should I apply this serum for best results?

Apply 2-3 drops to cleansed skin AM and PM, then follow with moisturizer and a broad-spectrum sunscreen.

Is this serum suitable for sensitive skin?

Yes. It is fragrance-free and hydroquinone-free, but users should patch test and stop use if irritation occurs.

What are the key active ingredients and their roles?

It contains tranexamic acid 3% to reduce discoloration, niacinamide 5% to brighten and soothe, and HEPES 5% to accelerate renewal.

When can I expect to see improvements?

Visible improvements may be seen in about two weeks with daily use, but results vary by individual.

Can Discoloration Defense be used with retinol?

Yes. It can be combined with a gentle retinol at night; avoid simultaneous use with other strong actives and use sunscreen daily.

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Lipo Lab South Africa

SkinCeuticals Discoloration Defense Serum

R 2,600.00

~~R 2,950.00~~ R 2,600.00

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Quantity

Lightweight serum designed to reduce the appearance of dark spots and even skin tone. Suitable for people who want a targeted brightening step that can be used alongside their daily skincare routine.

At a glance

Skin types: all (including oily, acne-prone, sensitive and mature)
Concerns: uneven skin tone, post‑inflammatory hyperpigmentation, sun spots, melasma
Size: 30 ml
Texture: silky, fast-absorbing serum
Fragrance: fragrance-free
Vegan-friendly and not tested on animals

What it is

Product	Size	Primary purpose
Discoloration Defense Serum	30 ml	Targets areas of uneven pigmentation to improve overall clarity and balance of skin tone

How to use

AM: Cleanse, then apply 2–3 drops over the face and areas of concern. Follow with your moisturiser and finish with an SPF when heading outdoors. For daytime protection, apply an appropriate SPF.
PM: Cleanse, apply 2–3 drops, then follow with a moisturiser. Use as part of your evening routine.
Start gradually if you have sensitive skin (every other day), then increase frequency as tolerated. Perform a patch test before first use.

Why it works

Tranexamic acid (3%) — helps reduce the appearance of persistent brown patches by addressing pigment-promoting pathways.
Niacinamide (5%) — brightens and soothes, helping to refine tone and support the skin barrier.
HEPES (5%) — supports gentle renewal of surface skin cells to improve texture and clarity.

What to expect

Texture: lightweight, non-sticky finish that layers easily under moisturiser and sunscreen.
Initial response: some users notice smoother, brighter-looking skin within several weeks; results vary and depend on consistent use.
If you experience persistent irritation, reduce frequency or discontinue and consult a clinician.

Good to know

Always patch test new products before applying to the whole face.
If you are pregnant, breastfeeding or under specialist care, check with your healthcare professional before use.
Avoid mixing with strong exfoliating acids or high‑strength retinoids until you know how your skin tolerates the combination.
Stop use if persistent redness or severe irritation occurs and seek professional advice.

Ingredients (INCI)

See packaging for full INCI list.

Storage & care

Store in a cool, dry place away from direct sunlight.
Keep the pump sealed between uses to protect active ingredients.
Do not expose to excessive heat.

Shipping & returns

Fast, tracked delivery nationwide (2–5 business days). Orders are typically dispatched within 1–2 business days.

Explore the full SkinCeuticals range for complementary products and routines: SkinCeuticals collection

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SkinCeuticals Discoloration Defense Serum